This course is designed for graduate students who are interested in conducting or better interpreting epidemiological studies relating genetics to dietary intakes, disease, or health. There is an increasing awareness that various aspects of diet and genetics may both be important contributing factors in chronic disease. This course provides an overview of the statistical tools available to conduct and interpret genetic association analyses of complex disease, with a focus on nutrition. We also review the strengths and weaknesses of the available methods, and provide hands-on experience applying methods such as genome-wide association, haplotype, RNA-sequencing, and gene-diet interaction analyses. Students will become familiar with the Tufts Computing Cluster, Unix tools, R, and other specialized genetic software.