<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="6.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">J S Buell</style></author><author><style face="normal" font="default" size="100%">Bess {Dawson-Hughes}</style></author><author><style face="normal" font="default" size="100%">Tammy M Scott</style></author><author><style face="normal" font="default" size="100%">D E Weiner</style></author><author><style face="normal" font="default" size="100%">Gerard E Dallal</style></author><author><style face="normal" font="default" size="100%">W Q Qui</style></author><author><style face="normal" font="default" size="100%">P Bergethon</style></author><author><style face="normal" font="default" size="100%">Irwin H Rosenberg</style></author><author><style face="normal" font="default" size="100%">M F Folstein</style></author><author><style face="normal" font="default" size="100%">S Patz</style></author><author><style face="normal" font="default" size="100%">R A Bhadelia</style></author><author><style face="normal" font="default" size="100%">Katherine L Tucker</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">25-Hydroxyvitamin D, dementia, and cerebrovascular pathology in elders receiving home services</style></title><secondary-title><style face="normal" font="default" size="100%">Neurology</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">80 and over</style></keyword><keyword><style  face="normal" font="default" size="100%">Aged</style></keyword><keyword><style  face="normal" font="default" size="100%">Alzheimer Disease</style></keyword><keyword><style  face="normal" font="default" size="100%">Body Mass Index</style></keyword><keyword><style  face="normal" font="default" size="100%">Confidence Intervals</style></keyword><keyword><style  face="normal" font="default" size="100%">Dementia</style></keyword><keyword><style  face="normal" font="default" size="100%">Female</style></keyword><keyword><style  face="normal" font="default" size="100%">Humans</style></keyword><keyword><style  face="normal" font="default" size="100%">Logistic Models</style></keyword><keyword><style  face="normal" font="default" size="100%">Magnetic Resonance Imaging</style></keyword><keyword><style  face="normal" font="default" size="100%">Male</style></keyword><keyword><style  face="normal" font="default" size="100%">Neurologic Examination</style></keyword><keyword><style  face="normal" font="default" size="100%">Odds Ratio</style></keyword><keyword><style  face="normal" font="default" size="100%">Phlebotomy</style></keyword><keyword><style  face="normal" font="default" size="100%">Retrospective Studies</style></keyword><keyword><style  face="normal" font="default" size="100%">Risk Factors</style></keyword><keyword><style  face="normal" font="default" size="100%">Stroke</style></keyword><keyword><style  face="normal" font="default" size="100%">Temporal Lobe</style></keyword><keyword><style  face="normal" font="default" size="100%">Vitamin D</style></keyword><keyword><style  face="normal" font="default" size="100%">Vitamin D Deficiency</style></keyword><keyword><style  face="normal" font="default" size="100%">{Cross-Sectional} Studies</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2010</style></year></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://www.ncbi.nlm.nih.gov/pubmed/19940273</style></url></web-urls></urls><number><style face="normal" font="default" size="100%">1</style></number><volume><style face="normal" font="default" size="100%">74</style></volume><pages><style face="normal" font="default" size="100%">18–26</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">BACKGROUND Vitamin D deficiency has potential adverse effects on neurocognitive health and subcortical function. However, no studies have examined the association between vitamin D status, dementia, and cranial MRI indicators of cerebrovascular disease (CVD).
METHODS Cross-sectional investigation of 25-hydroxyvitamin D [25(OH)D], dementia, and MRI measures of CVD in elders receiving home care (aged 65-99 years) from 2003 to 2007.
RESULTS Among 318 participants, the mean age was 73.5 +/- 8.1 years, 231 (72.6%) were women, and 109 (34.3%) were black. 25(OH)D concentrations were deficient (&lt;10 {ng/mL)} in 14.5% and insufficient (10-20 ng/mL) in 44.3% of participants. There were 76 participants (23.9%) with dementia, 41 of which were classified as probable AD. Mean 25(OH)D concentrations were lower in subjects with dementia (16.8 vs 20.0 ng/mL, p &lt; 0.01). There was a higher prevalence of dementia among participants with 25(OH)D insufficiency (&lt; or =20 ng/mL) (30.5% vs 14.5%, p &lt; 0.01). 25(OH)D deficiency was associated with increased white matter hyperintensity volume (4.9 vs 2.9 mL, p &lt; 0.01), grade (3.0 vs 2.2</style></abstract><notes><style face="normal" font="default" size="100%">{PMID:} 19940273</style></notes></record></records></xml>