<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="6.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Sarah E Anderson</style></author><author><style face="normal" font="default" size="100%">Patricia Cohen</style></author><author><style face="normal" font="default" size="100%">Elena N Naumova</style></author><author><style face="normal" font="default" size="100%">Paul F. Jacques</style></author><author><style face="normal" font="default" size="100%">Aviva Must</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Adolescent obesity and risk for subsequent major depressive disorder and anxiety disorder: prospective evidence</style></title><secondary-title><style face="normal" font="default" size="100%">Psychosomatic Medicine</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Adolescent</style></keyword><keyword><style  face="normal" font="default" size="100%">Adult</style></keyword><keyword><style  face="normal" font="default" size="100%">Anxiety Disorders</style></keyword><keyword><style  face="normal" font="default" size="100%">Child</style></keyword><keyword><style  face="normal" font="default" size="100%">Cohort Studies</style></keyword><keyword><style  face="normal" font="default" size="100%">Depressive Disorder</style></keyword><keyword><style  face="normal" font="default" size="100%">Female</style></keyword><keyword><style  face="normal" font="default" size="100%">Humans</style></keyword><keyword><style  face="normal" font="default" size="100%">Major</style></keyword><keyword><style  face="normal" font="default" size="100%">Male</style></keyword><keyword><style  face="normal" font="default" size="100%">Obesity</style></keyword><keyword><style  face="normal" font="default" size="100%">Prospective Studies</style></keyword><keyword><style  face="normal" font="default" size="100%">Risk Factors</style></keyword><keyword><style  face="normal" font="default" size="100%">Sex Factors</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2007</style></year></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://www.ncbi.nlm.nih.gov/pubmed/17942847</style></url></web-urls></urls><number><style face="normal" font="default" size="100%">8</style></number><volume><style face="normal" font="default" size="100%">69</style></volume><pages><style face="normal" font="default" size="100%">740–747</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">OBJECTIVE To} assess whether adolescent obesity is associated with risk for development of major depressive disorder {(MDD)} or anxiety disorder. Obesity has been linked to psychosocial difficulties among youth.
METHODS Analysis of a prospective community-based cohort originally from upstate New York, assessed four times over 20 years. Participants (n = 776) were 9 to 18 years old in 1983; subsequent assessments took place in 1985 to 1986 (n = 775), 1991 to 1994 (n = 776), and 2001 to 2003 (n = 661). Using Cox proportional hazards analysis, we evaluated the association of adolescent (age range, 12-17.99 years) weight status with risk for subsequent {MDD} or anxiety disorder (assessed at each wave by structured diagnostic interviews) in males and females. A total of 701 participants were not missing data on adolescent weight status and had &amp;gt; or = 1 subsequent assessments. {MDD} and anxiety disorder analyses included 674 and 559 participants (free of current or previous {MDD} or anxiety disorder), respectively. Adolescent obesity was defined as body mass index above the age- and gender-specific 95th percentile of the Centers for Disease Control and Prevention growth reference.
RESULTS Adolescent obesity in females predicted an increased risk for subsequent {MDD} (adjusted hazard ratio {(HR)} = 3.9; 95% confidence interval {(CI)} = 1.3, 11.8) and for anxiety disorder {(HR} = 3.8; {CI} = 1.3, 11.3). Adolescent obesity in males was not statistically significantly associated with risk for {MDD} {(HR} = 1.5; {CI} = 0.5, 3.5) or anxiety disorder {(HR} = 0.7; {CI} = 0.2, 2.9).
CONCLUSION Females obese as adolescents may be at increased risk for development of depression or anxiety disorders.</style></abstract><notes><style face="normal" font="default" size="100%">{PMID:} 17942847</style></notes></record></records></xml>