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Accumulation of mitochondrial DNA deletions is age, tissue and folate-dependent in rats." Mutation Research. 2005;570:63-70."
Chronic cigarette smoking is associated with diminished folate status, altered folate form distribution, and increased genetic damage in the buccal mucosa of healthy adults." The American Journal of Clinical Nutrition. 2006;83:835-841."
A comparison of carotenoids, retinoids, and tocopherols in the serum and buccal mucosa of chronic cigarette smokers versus nonsmokers." Cancer Epidemiology, Biomarkers & Prevention: A Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology. 2006;15:993-999."
Folate depletion in human lymphocytes up-regulates p53 expression despite marked induction of strand breaks in exons 5-8 of the gene." Mutation Research. 2007;626:171-179."
Folic acid and vitamin B-12 supplementation does not favorably influence uracil incorporation and promoter methylation in rectal mucosa DNA of subjects with previous colorectal adenomas." The Journal of Nutrition. 2007;137:2114-2120."
Mild depletion of dietary folate combined with other B vitamins alters multiple components of the Wnt pathway in mouse colon." The Journal of Nutrition. 2007;137:2701-2708."
Older age and dietary folate are determinants of genomic and p16-specific DNA methylation in mouse colon." The Journal of Nutrition. 2007;137:1713-1717."
Associations between single nucleotide polymorphisms in folate uptake and metabolizing genes with blood folate, homocysteine, and DNA uracil concentrations." The American Journal of Clinical Nutrition. 2008;88:1149-1158."
Moderate folate depletion modulates the expression of selected genes involved in cell cycle, intracellular signaling and folate uptake in human colonic epithelial cell lines." The Journal of Nutritional Biochemistry. 2008;19:328-335."
Multiple B-vitamin inadequacy amplifies alterations induced by folate depletion in p53 expression and its downstream effector MDM2." International Journal of Cancer. Journal International Du Cancer. 2008;123:519-525."
Polymorphisms in uracil-processing genes, but not one-carbon nutrients, are associated with altered DNA uracil concentrations in an urban Puerto Rican population." The American Journal of Clinical Nutrition. 2009;89:1927-1936."
MAT1A variants are associated with hypertension, stroke, and markers of DNA damage and are modulated by plasma vitamin B-6 and folate." The American Journal of Clinical Nutrition. 2010;91:1377-1386."
Combined inadequacies of multiple B vitamins amplify colonic Wnt signaling and promote intestinal tumorigenesis in BAT-LacZxApc1638N mice." The FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology. 2011;25:3136-3145."
Diet-induced obesity elevates colonic TNF-α in mice and is accompanied by an activation of Wnt signaling: a mechanism for obesity-associated colorectal cancer." The Journal of Nutritional Biochemistry. 2011."
Maternal one-carbon nutrient intake and cancer risk in offspring." Nutrition Reviews. 2011;69:561-571."
The Folate Hydrolase 1561C>T Polymorphism Is Associated With Depressive Symptoms in Puerto Rican Adults." Psychosomatic Medicine. 2011."