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Filters: Author is Zhenhua Liu [Clear All Filters]
Ageing, chronic alcohol consumption and folate are determinants of genomic DNA methylation, p16 promoter methylation and the expression of p16 in the mouse colon." The British Journal of Nutrition. 2010;104:24-30."
Altered folate availability modifies the molecular environment of the human colorectum: implications for colorectal carcinogenesis." Cancer Prevention Research . 2011;4:530-543."
Associations between single nucleotide polymorphisms in folate uptake and metabolizing genes with blood folate, homocysteine, and DNA uracil concentrations." The American Journal of Clinical Nutrition. 2008;88:1149-1158."
Chronic cigarette smoking is associated with diminished folate status, altered folate form distribution, and increased genetic damage in the buccal mucosa of healthy adults." The American Journal of Clinical Nutrition. 2006;83:835-841."
Combined inadequacies of multiple B vitamins amplify colonic Wnt signaling and promote intestinal tumorigenesis in BAT-LacZxApc1638N mice." The FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology. 2011;25:3136-3145."
A comparison of carotenoids, retinoids, and tocopherols in the serum and buccal mucosa of chronic cigarette smokers versus nonsmokers." Cancer Epidemiology, Biomarkers & Prevention: A Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology. 2006;15:993-999."
Diet-induced obesity elevates colonic TNF-α in mice and is accompanied by an activation of Wnt signaling: a mechanism for obesity-associated colorectal cancer." The Journal of Nutritional Biochemistry. 2011."
Folate depletion in human lymphocytes up-regulates p53 expression despite marked induction of strand breaks in exons 5-8 of the gene." Mutation Research. 2007;626:171-179."
Folate supplementation differently affects uracil content in DNA in the mouse colon and liver." The British Journal of Nutrition. 2011;105:688-693."
Mild depletion of dietary folate combined with other B vitamins alters multiple components of the Wnt pathway in mouse colon." The Journal of Nutrition. 2007;137:2701-2708."
Moderate folate depletion modulates the expression of selected genes involved in cell cycle, intracellular signaling and folate uptake in human colonic epithelial cell lines." The Journal of Nutritional Biochemistry. 2008;19:328-335."
Multiple B-vitamin inadequacy amplifies alterations induced by folate depletion in p53 expression and its downstream effector MDM2." International Journal of Cancer. Journal International Du Cancer. 2008;123:519-525."
Older age and dietary folate are determinants of genomic and p16-specific DNA methylation in mouse colon." The Journal of Nutrition. 2007;137:1713-1717."
Other one-carbon micronutrients and age modulate the effects of folate on colorectal carcinogenesis." Nutrition Reviews. 2008;66 Suppl 1:S15-17."
Polymorphisms in uracil-processing genes, but not one-carbon nutrients, are associated with altered DNA uracil concentrations in an urban Puerto Rican population." The American Journal of Clinical Nutrition. 2009;89:1927-1936."