Faculty Publications

Wang X-D. "Can smoke-exposed ferrets be utilized to unravel the mechanisms of action of lycopene?" The Journal of Nutrition. 2005;135:2053S-6S.

Wang X-D. "Alcohol, vitamin A, and cancer." Alcohol. 2005;35:251-258.

Lian F, Kang-Quan, Russell RM, Wang X-D. "Beta-cryptoxanthin suppresses the growth of immortalized human bronchial epithelial cells and non-small-cell lung cancer cells and up-regulates retinoic acid receptor beta expression." International Journal of Cancer. Journal International Du Cancer. 2006;119:2084-2089. Abstract

Kim Y, Liu XS, Liu C, Smith DE, Russell RM, Wang X-D. "Induction of pulmonary neoplasia in the smoke-exposed ferret by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK): a model for human lung cancer." Cancer Letters. 2006;234:209-219. Abstract

Liu C, Russell RM, Wang X-D. "Lycopene supplementation prevents smoke-induced changes in p53, p53 phosphorylation, cell proliferation, and apoptosis in the gastric mucosa of ferrets." The Journal of Nutrition. 2006;136:106-111. Abstract

Kang-Quan, Liu C, Ernst H, Krinsky NI, Russell RM, Wang X-D. "The biochemical characterization of ferret carotene-9',10'-monooxygenase catalyzing cleavage of carotenoids in vitro and in vivo." The Journal of Biological Chemistry. 2006;281:19327-19338. Abstract

Kim Y, Chongviriyaphan N, Liu C, Russell RM, Wang X-D. "Combined antioxidant (beta-carotene, alpha-tocopherol and ascorbic acid) supplementation increases the levels of lung retinoic acid and inhibits the activation of mitogen-activated protein kinase in the ferret lung cancer model." Carcinogenesis. 2006;27:1410-1419. Abstract

Lian F, Smith DE, Ernst H, Russell RM, Wang X-D. "Apo-10'-lycopenoic acid inhibits lung cancer cell growth in vitro, and suppresses lung tumorigenesis in the A/J mouse model in vivo." Carcinogenesis. 2007;28:1567-1574. Abstract

H M, Wang X-D. "The bioconversion of carotenoids into retinoids: Implications for cancer prevention." In: IT L, ed. Vitamin A: New Research. Hauppauge, NY: Nova Science Publishers; 2007:.

Kim Y, Lian F, Yeum K-J, et al. "The effects of combined antioxidant (beta-carotene, alpha-tocopherol and ascorbic acid) supplementation on antioxidant capacity, DNA single-strand breaks and levels of insulin-like growth factor-1/IGF-binding protein 3 in the ferret model of lung canc." International Journal of Cancer. Journal International Du Cancer. 2007;120:1847-1854. Abstract

Mernitz H, Smith DE, Wood RJ, Russell RM, Wang X-D. "Inhibition of lung carcinogenesis by 1alpha,25-dihydroxyvitamin D3 and 9-cis retinoic acid in the A/J mouse model: evidence of retinoid mitigation of vitamin D toxicity." International Journal of Cancer. Journal International Du Cancer. 2007;120:1402-1409. Abstract

Lian F, Smith DE, Ernst H, Russell RM, Wang X-D. "Apo-10'-lycopenoic acid inhibits lung cancer cell growth in vitro, and suppresses lung tumorigenesis in the A/J mouse model in vivo." Carcinogenesis. 2007;28:1567-1574. Abstract

Fu X, Wang X-D, Mernitz H, Wallin R, Shea KM, Booth SL. "9-Cis retinoic acid reduces 1alpha,25-dihydroxycholecalciferol-induced renal calcification by altering vitamin K-dependent gamma-carboxylation of matrix gamma-carboxyglutamic acid protein in A/J male mice." The Journal of Nutrition. 2008;138:2337-2341. Abstract

Mein JR, Lian F, Wang X-D. "Biological activity of lycopene metabolites: implications for cancer prevention." Nutrition Reviews. 2008;66:667-683. Abstract

Wang Y, Ausman LM, Russell RM, Greenberg AS, Wang X-D. "Increased apoptosis in high-fat diet-induced nonalcoholic steatohepatitis in rats is associated with c-Jun NH2-terminal kinase activation and elevated proapoptotic Bax." The Journal of Nutrition. 2008;138:1866-1871. Abstract

Lian F, Wang X-D. "Lycopene and Lung Cancer." In: VR P, RR W, eds. Lycopene: Nutritional, Medical and Therapeutic Properties. Enfield, NH: Science Publishers press; 2008:.