Students will explore the fundamental roles of nutrients in biological systems and the implications of macronutrient biological functions on food and nutrition policy. Emphasis will be placed on the function of nutrients as defined by their chemistry, interrelations among nutrient functions, mechanistic approaches in the analysis of nutrient‐disease relationships, and recent advances in the basic sciences related to nutrition and nutrient function. The course will integrate examples of community, clinical and public health policy applications throughout the term. Published journal articles from the peer reviewed literature, case histories, and public policy documents will form the basis for critical review and discussion. This is the first of a two course sequence (NUTB 205 and NUTB 305 – may be taken in either order).